Hypothyroidism can cause fatigue, constipation, hair loss, dry skin, depression, muscle aches, joint pains, insomnia, menstrual irregularities, poor memory, and weight gain. There are several thyroid medications available; including, Synthroid, Levothyroxine, Armour Thyroid, and Cytomel. Synthroid contains the hormone T4. This is the form of thyroid hormone that is relatively inactive. T4 converts to T3, which is the most active form of thyroid hormone. T4 also converts to reverse T3, which is like a brake on the system. Ideally, all three hormones are in balance with the medication one takes. However, some people produce too much reverse T3; this is usually because of diabetes, pre diabetes, high cortisol levels, low iodine or low iron. As reverse T3 increases, it puts a brake on your metabolism. These people either never feel different when they start a T4 only containing medication (Synthroid or Levothyroxine); or they feel better for awhile then hypothyroid symptoms recur. Some people feel worse immediately after the start of thyroid hormone replacement and this is usually secondary to an underlying adrenal problem. Some have started medications and have never noticed any improvement. As you can see, this is a very complicated problem that may require Armour Thyroid, iodine, phosphotidyl serine (to decrease cortisol), medications to drop insulin levels or even T3 by itself.

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